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13. Salmonella & Antibiotics

Antimicrobial agents are often ineffective at alleviating clinical symptoms of salmonellosis.  Antibiotics also can prolong shedding. The dissemination of multi-drug resistant Salmonella in pet rodents might have been facilitated by the use of prophylactic antimicrobials within the pocket-pet (e.g., hamsters, mice, and rats) animal industry. This use might have contributed to disease transmission in colonized animals and increased shedding of Salmonella.  As such, the use of antibiotics in raising these animals may have increased transmission among animals, from animals to their human caretakers, and from animals to the people who purchased these animals as pets.  Appropriate animal husbandry and hygiene practices, such as those used for the production of antibiotic-free laboratory rodents, could eliminate the need for non-therapeutic antimicrobials to prevent disease in rodents.




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