|You take stock of the current information on antibiotic use
in the rodents:
- It is not known whether the infectious agent(s) involved in
“non-specific rodent enteritis” are bacterial, viral, or
environmental. Diet and/or stress could be contributing factors
with this syndrome.
- The administration of antimicrobials for a Salmonella infection may
lead to prolonged shedding of organisms, which would tend to increase
transmission to both other rodents and to people.
- Every time an antimicrobial agent is administered, there is a
selective pressure for the survival of resistant strains. It would be
helpful if outbreaks of non-specific rodent enteritis were cultured and
antimicrobial susceptibility tests run on targeted pathogens before
administration of an antimicrobial agent.
- Salmonella infections may be controlled but not always eliminated
when antibiotics are administered to infected rodents. Customers
who purchase animals do not continue to administer these antibiotics;
therefore, the animal may become clinically ill soon after being
purchased. A general rule with Salmonella is that clinically ill
animals tend to shed in greater numbers than do animals with