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15. Antibiotic Summary


You take stock of the current information on antibiotic use in the rodents:
  1. It is not known whether the infectious agent(s) involved in “non-specific rodent enteritis” are bacterial, viral, or environmental.  Diet and/or stress could be contributing factors with this syndrome.

  2. The administration of antimicrobials for a Salmonella infection may lead to prolonged shedding of organisms, which would tend to increase transmission to both other rodents and to people.

  3. Every time an antimicrobial agent is administered, there is a selective pressure for the survival of resistant strains. It would be helpful if outbreaks of non-specific rodent enteritis were cultured and antimicrobial susceptibility tests run on targeted pathogens before administration of an antimicrobial agent. 

  4. Salmonella infections may be controlled but not always eliminated when antibiotics are administered to infected rodents.  Customers who purchase animals do not continue to administer these antibiotics; therefore, the animal may become clinically ill soon after being purchased. A general rule with Salmonella is that clinically ill animals tend to shed in greater numbers than do animals with subclinical infections.



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