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Examples of Antimicrobials Important in Human Medicine Being Used for Animal Treatment, Metaphylaxis or Growth Promotion

A wide array of antimicrobial classes that are used for animal health and production are also used for human treatments. Those AMR genes that propagate from the use of antibiotics for animal populations may spread and eventually hurt the efficacy of these same antibiotic when they are used to treat people. While all AMR is a potential human health hazard, the preserved efficacy of some human medicine antibiotics is is of higher priority.  Below is a list of antimicrobials used for both animals and humans, classified by the World Health Organization according to their importance to human health

 

A. Classified By The World Health Organization As CRITICALLY IMPORTANT For Humans

 

Antibiotic classes

ANIMALS

 

Humans

Species

Disease treatment

Disease Prevention

Growth promotion

Aminoclycosides: gentamicin, neomycin, streptomycin

Beef cattle, goats, poultry, sheep, swine, certain plants

Yes

Yes

 

Yes

Penicillins: amoxicillin, ampicillin

Beef cattle, dairy cows, fowl, poultry, sheep, swine

Yes

Yes

Yes

Yes

Cephalosporins, third generation: ceftiofur

Beef cattle, dairy cows, poultry, sheep, swine

Yes

Yes

 

Yes

Glycopeptides: Avoparcin, vancomycin

 

Poultry, swine

 

 

Yes

Yes

Macrolides: erythromycin, tilmicosin, tylosin

 

Beef cattle, poultry, swine

Yes

Yes

Yes

Yes

Quinolones: (fluoroquinolones) sarafloxacin, enrofloxaxin

 

Beef cattle, poultry

Yes

Yes

 

Yes

 

Streptogramins: Virginiamycin, quinupristin-dalfopristin

Beef cattle, poultry, swine

Yes

Yes

Yes

Yes

Carbapenems, lipopeptides, oxazolidinones, cycloserine, ethambutol, ethionamide, isoniazid, para-aminosalicyclic acid, pyrazinamide

 

 

 

 

Yes

 

 

 

 

B. Classified By The World Health Organization As HIGHLY IMPORTANT For Humans

 

Antibiotic classes

ANIMALS

 

Humans

Species

Disease treatment

Disease Prevention

Growth promotion

Cephalosporins, first generation: cefadroxil

 

 

 

 

 

Yes

Cephalosporins, second generation: cefuroxime

 

 

 

 

Yes

Spectinomycin

 

Poultry, swine

 

Yes

 

Yes

Sulfonamides: sulfadimethoxine, sulfamethazine, sulfisoxazole

Beef cattle, dairy cows, fowl, poultry, swine, catfish, trout, salmon

Yes

 

Yes

Yes

Tetracyclines: Chlortetracycline, oxytetracycline, tetracycline

Beef cattle, dairy cows, honey bees, poultry, sheep, swine, catfish, trout, salmon, lobster

Yes

Yes

Yes

Yes

Cephamycins, dofazimine, monobactams, amino-penicillins, antipseudomonal penicillins, sulfones

 

 

 

 

 

Yes

 

 

 


 

C. Classified By The World Health Organization As IMPORTANT For Humans

 

Antibiotic classes

ANIMALS

 

Humans

Species

Disease treatment

Disease Prevention

Growth promotion

Polypeptides: Bacitracin

 

Fowl, poultry, swine

Yes

Yes

Yes

Yes

Lincosamides: Lincomycin

 

Poultry, swine

Yes

Yes

 

Yes

 

 

 

 

D. Not known to be used in humans

 

Antibiotic classes

ANIMALS

 

Humans

Species

Disease treatment

Disease Prevention

Growth promotion

Babermycin: Flavomycin

 

Beef cattle, poultry, swine

 

Yes

Yes

 

Ionophores: monensin, salinomycin, semduramicin, lasalocid

Beef cattle, fowl, goats, poultry, rabbits, sheep

 

Yes

Yes

 

 

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